The Picornaviruses
Ehrenfeld, Ellie, Domingo, Esteban, Roos, Raymond PA springboard for developing new approaches to understanding, preventing, and treating picornaviral diseases.
- Examines the most current breakthroughs as well as the challenges that lie ahead in picornavirus research; encapsulates current knowledge of the molecular biology, evolution, and pathogenesis of this large family of viruses; and, examines the diseases that these viruses cause and the latest vaccines and antiviral drugs to prevent and control those diseases.
- Explores the structural and mechanistic bases of picornavirus replication, highlighting new insights about the host cell interactions needed for virus growth; and, illustrates how the regular occurrence of mutations, typical of viruses with RNA as genetic material, generates the quasispecies dynamics that underlie viral fitness.
- Focuses on picornaviruses that cause disease, examining pathogenicity and innate and acquired immune responses against infection as well as the latest vaccine and antiviral drug strategies.
Категории:
Година:
2010
Издание:
1
Издателство:
ASM Press
Език:
english
Страници:
493
ISBN 10:
1555816037
ISBN 13:
9781555816032
Файл:
PDF, 18.99 MB
IPFS:
,
english, 2010